Category: PANS

What is PANS/PANDAS and Why Should You Care?

The following content is sponsored by the Pace Foundation

PANS/PANDAS Infographic

The PACE Foundation

What is PANS/PANDAS and Why Should You Care?

Picture this—one moment, you have a healthy, carefree child. Then, overnight, your child becomes a different person. Now they’re moody, anxious, aggressive, compulsively obsessing over trivial things, or restricting their eating.

If this sounds familiar, your child may have Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) or Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Disease (PANDAS).

This graphic, sponsored by the PACE Foundation, shares six important facts you should know about PANS/PANDAS, and illustrates how your individual or corporate donations could help cure these autoimmune disorders.

PANS/PANDAS: An Overview

PANS and PANDAS are types of Children’s Postinfectious Autoimmune Encephalopathy (CPAE), which is when your immune system stops functioning properly and starts attacking healthy cells in your body.

These particular autoimmune disorders are triggered by an infection such as strep throat or other streptococcal infections. Below, we’ll dive into six important things to know if you think your child is suffering from either of these autoimmune disorders.


PANS/PANDAS is a pediatric disorder

According to the National Institute of Mental Health (NIMH), PANS/PANDAS is considered a pediatric disorder because it’s most commonly found in children from age three to puberty.

While occurrences in teenagers and adults are possible, they’re extremely rare based on current research. Children that develop PANS/PANDAS are believed to be genetically susceptible to it.


PANS/PANDAS is a clinical diagnosis

PANS/PANDAs cannot be detected in a lab (Read more...)

Autoimmune Disorders: Is Your Child At Risk of PANS or PANDAS?

The following content is sponsored by The Pace Foundation.


Autoimmune Disorders: Is Your Child At Risk of PANS or PANDAS?

Every year, millions of young children and adolescents get sick with the flu, or some sort of viral or bacterial infection.

For a small number of children, these infections trigger an autoimmune response that causes acute behavior changes. This response is called Children’s Postinfectious Autoimmune Encephalopathy (CPAE), and its symptoms appear similar to OCD or severe anxiety.

How can you tell if your child is suffering from a CPAE? This graphic, presented by the PACE Foundation, outlines the two types of CPAEs—PANS and PANDAS—and explains what symptoms to look for, and where to seek help if needed.

What is CPAE?

CPAE is a type of autoimmune disorder that causes your immune system to accidentally attack healthy cells. In the case of CPAE, this reaction is triggered by an infection.

The area of the body that’s affected by CPAE is the brain. Specifically, it attacks the basal ganglia, which is the same region of the brain that’s been linked to OCD and Tourette’s syndrome.

To date, there are two types of CPAEs:

  • PANS (Pediatric acute-onset neuropsychiatric syndrome): A sudden onset of OCD-like symptoms, thought to be triggered by infections or inflammatory reactions.
  • PANDAS (Pediatric autoimmune neuropsychiatric disorder associated with streptococcus): A subset of PANs, characterized by an acute onset of OCD or tics. It’s caused by a streptococcal infection like strep throat.

Some key symptoms to look out for (Read more...)