Day: August 14, 2022

Psychedelics: What a Long Strange Trip It’s Been…



The numbers are staggering. An estimated twelve million Americans suffer from post-traumatic stress disorder (PTSD) according to data from the U.S. Department of Veterans Affairs, approximately 37% of whom are considered to have severe symptoms. At some point in our lives, six in ten men and five in ten women will experience meaningful trauma; approximately 6% of the population will go onto to suffer with PTSD. While the causes of PTSD are relatively easy to identify (combat, accidents, assault, etc), the symptoms can reveal themselves in confounding ways and the treatment modalities can be frustratingly ineffective for many. Data from the National Institute of Mental Health show greater prevalence of PTSD among women and with older Americans.

The healthcare industry has had a complicated history with developing proper therapeutic treatments for PTSD. Given the extraordinary urgency and overwhelming need, in part due to the trauma in war zones in Iraq/Afghanistan/Ukraine/Middle East, severely limited behavioral and mental health resources, and issues associated with the pandemic, there has been a renewed interest in psychedelics. Recent estimates from the Substance Abuse and Mental Health Services Administration showed that over $280 billion is spent annually on treatment services for mental health and substance use disorders, and this is barely adequate. While the most effective treatment for many is “talk therapy,” the healthcare system today simply does not have enough providers.

In response, the biotech industry has started to embrace a class of mind-altering compounds such as psilocybin, lysergic acid diethylamide (LSD), and 3,4-methylenedioxymethamphetamine (MDMA (Read more...)

Sunday Reads And Listens


This post is by Howard Lindzon from Howard Lindzon


Good morning everyone.

I am in Calabasas, just north of LA for the day and heading out on a grueling 53 mile ride with my pals Mike Dean and Roy Rubin. More training for my rides coming up in the Alps.

Ellen and I had the joy of having my daughter Rachel home for a few weeks, but she just headed back to the upper east side of New York.

Rachel left me with the latest book she read ‘No One Asked For This‘ written by Larry David’s daughter Cazzie David. So far it is very funny.

On the podcast side I really laughed out loud a lot listening to Jeff Ross and Conan O’Brien.

I really enjoyed the series ‘The Bear’ on HULU. Brian Kopelman interviews Christopher Storer, the creatpor on his podcast The Moment.

My partner Charlie has a great post out titled ‘How To Think About Investing During A Recession’.

Here is a latest and very good conversation with Howard Marks on investing in today’s markets.

Have a great Sunday.