How to Engineer Biology

Because biology is the result of evolution and not human development, bringing engineering principles to it is guaranteed to fail. Or so goes the argument behind the “Grove fallacy,” first invoked by drug industry observer Derek Lowe in a critique …

Debating Crypto: Katie Haun vs. Paul Krugman (3 of 3)

watch time: 39 minutes

This “Let’s Settle This” debate (hosted by Versus by KIO Networks) between a16z crypto general partner Katie Haun and Nobel Prize-winning economist Paul Krugman took place in front of bankers, business leaders, and other audience members …

A Skeptic’s (Monetary Economist’s) View of Crypto (2 of 3)

watch time: 26 minutes

“What problem does it solve?” That’s the heart of Nobel-prize winning economist Paul Krugman’s skepticism around cryptocurrencies — noting that while he may not understand technology, he does understand monetary economics! — shared as part of …

3 Common Myths People Have About Crypto (1 of 3)

watch time: 36 minutes

Here are three common myths people that have when first hearing about crypto: that cryptocurrencies are anonymous (and therefore more likely to be used by criminals); that there’s no real use case (aside from speculation); and …

Why Direct Sales Always Matters in the Enterprise

0/ Traditional enterprise GTM strategies are being eaten from the bottom by bottom-up adoption (SaaS, open source, dev tooling) and from the top by services.

Fundraising Advice to Avoid

0/ Questionable fund raising advice you may want to think twice about before following. A thread.

1/ As an entrepreneur I had to raise money many times. Not knowing what I was doing, I’d follow popular advice on the topic. …

a16z Podcast: How to Manage a PR Agency

One of the company building topics that’s surprisingly mystifying is PR — and only surprising since so much of the strategy and tactics behind public relations are actually hidden from public view. We’ve tried demystifying the topic in an ongoing …